Impact of a community-based multiple risk factor intervention on cardiovascular risk in black families with a history of premature coronary disease.

نویسندگان

  • Diane M Becker
  • Lisa R Yanek
  • Wallace R Johnson
  • Diane Garrett
  • Taryn F Moy
  • Stasia Stott Reynolds
  • Roger S Blumenthal
  • Dhananjay Vaidya
  • Lewis C Becker
چکیده

BACKGROUND Black subjects with a family history of premature coronary heart disease (CHD) have a marked excess risk, yet barriers prevent effective risk reduction. We tested a community-based multiple risk factor intervention (community-based care [CBC]) and compared it with "enhanced" primary care (EPC) to reduce CHD risk in high-risk black families. METHODS AND RESULTS Black 30- to 59-year-old siblings of a proband with CHD aged <60 years were randomized for care of BP > or =140/90 mm Hg, LDL cholesterol > or =3.37 mmol/L, or current smoking to EPC (n=168) or CBC (n=196) and monitored for 1 year. EPC and CBC were designed to eliminate barriers to care. The CBC group received care by a nurse practitioner and a community health worker in a community setting. The CBC group was 2 times more likely to achieve goal levels of LDL cholesterol and blood pressure compared with the EPC group (95% CI, 1.11 to 4.20 and 1.39 to 3.88, respectively) with adjustment for baseline levels of age, sex, education, and baseline use of medications. The CBC group demonstrated a significant reduction in global CHD risk, whereas no reduction was seen in the EPC group (P<0.0001). CONCLUSIONS Eliminating known barriers may not be sufficient to reduce CHD risk in primary care settings. An alternative community care model that addresses barriers may be a more effective way to ameliorate CHD risk in high-risk black families.

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عنوان ژورنال:
  • Circulation

دوره 111 10  شماره 

صفحات  -

تاریخ انتشار 2005